ENTEROSURE^® for Layers

Proven Probiotic Power for Egg Shell Quality and Gut Health

ENTEROSURE is a proprietary multi-strain probiotic blend designed to support intestinal health and optimize performance in laying hens. With a scientifically backed combination of Bacillus strains, ENTEROSURE promotes a resilient gut microbiome, enhances eggshell quality, and improves skeletal strength – delivering benefits that matter to both producers and consumers.^1-3

Why ENTEROSURE?

• Supports a Healthy Microbiome

The Bacillus strains in ENTEROSURE help inhibit harmful pathogens like Clostridium perfringens, Salmonella, and Escherichia coli, while promoting beneficial bacteria such as Lactobacilli and Bifidobacteria.^4-6,8

• Improves Eggshell Quality

In controlled trials, hens supplemented with ENTEROSURE showed significantly stronger eggshells and improved shell thickness at multiple stages of production.^4,5

• Enhances Bone Strength

ENTEROSURE supplementation led to measurable improvements in tibia weight, density, and calcium content – critical for long-term hen health and productivity.⁷

• Heat-Stable & Versatile

Formulated to remain effective during pelleting, packing, and storage. Compatible with a wide range of feed ingredients, organic acids, and most antibiotics.⁹

Mode of Action

ENTEROSURE is a proprietary blend of probiotic Bacillus strains. These strains secrete antimicrobial metabolites and quorum quenching molecules to directly inhibit and manage the growth of specific pathogenic bacteria and promote, restore, and maintain a healthy microbiome, enabling the product to manage intestinal health challenges and improve egg quality.^9-11

Product Specifications

• Recommended Inclusion Rate: 1 lb per ton of complete feed
• Packaging: 25 kg bags

Resources

References

¹Bacillus subtilis PB6 Inhibits a Broad Range of Clostridial Isolates From Poultry, Swine And Ruminants, WP-08-00049.
²Comparative Study of the Antimicrobial Activity of Anaeban™, VSL#3® and ALIGN™ Against C. Difficile and C. JejunI, WP-07-00036.
³Validation of ENTEROSURE™ in Commercial Production, TD-23-9069.
⁴The effect of multi-strain probiotic ENTEROSURE® on egg quality, tibia traits, and cecal microflora composition in layers, PTP-15519.
⁵Oketch, E. O., Yu, M., Hong, J. S., Chaturanga, N. C., Seo, E., Lee, H., Hermes, R. G., Smeets, N., Taechavasonyoo, A., Kirwan, S., Rodriguez-Sanchez, R., & Heo, J. M. (2024). Laying hen responses to multi-strain Bacillus-based probiotic supplementation from 25 to 37 weeks of age. Animal Bioscience, 37(8), 1418–1427. https://doi.org/10.5713/ab.23.0495
⁶Development of a new probiotic product inhibitory to Salmonella spp. and E. coli, WP-20-640.
⁷Efficacy of probiotics to control necrotic enteritis caused by Clostridium perfringens in broiler chickens when administered via feed, WP-21-1055
⁸Tajudeen H, Ha SH, Hosseindoust A, Mun JY, Park S, Park S, Choi P, Hermes RG, Taechavasonyoo A, Rodriguez R, Kim J. Effect of dietary inclusion of Bacillus-based probiotics on performance, egg quality, and the faecal microbiota of laying hen. Animal Bioscience. 2024 Apr;37(4):689-696. doi: 10.5713/ab.23.0299.
⁹Compatibility of ENTEROSURE with coccidiostats, antibiotics, chlorine and acidifier. SD-22-25231
¹⁰Sampath, V., Cho, S., Jeong, J. et al. Dietary Bacillus spp. supplementation to both sow and progenies improved post-weaning growth rate, gut function, and reduce the pro-inflammatory cytokine production in weaners challenged with Escherichia coli K88. Animal Microbiome 6, 3 (2024). https://doi.org/10.1186/s42523-024-00290-y
¹¹Teo AY, Tan HM. Inhibition of Clostridium perfringens by a novel strain of Bacillus subtilis isolated from the gastrointestinal tracts of healthy chickens. Applied & Environmental Microbiology. 2005 Aug;71(8):4185-90. doi: 10.1128/AEM.71.8.4185-4190.2005. 

Hy-Line^® is a registered trademark of Hy-Line International.

Have a Question?

If you have a question about our products or services, or just want more information, fill out the form below and someone on our team will be in contact with you.