ButiPEARL^®

Encapsulated Butyric Acid for a Healthy Swine and Poultry Gut

Take a closer look at our proprietary MicroPEARLS™ technology by watching the video below.

The Role of Butyric Acid for Swine and Poultry

Butyric acid is one of the short-chain fatty acids (SCFA) most efficiently used by the epithelial cells of the gastrointestinal (GI) tract. Butyric acid promotes the growth of tissues lining the GI tract and development of the intestinal epithelium in monogastric animals.^1,2 With the industry shift to reduce antibiotic use, encapsulated butyric acid has become a first-choice antibiotic alternative for broiler, layer, turkey and swine producers. Delivery of butyric acid to the small intestine can improve the tight junctions, strengthening the intestinal barrier with upregulation of tight junction proteins. By strengthening the barrier and aiding in barrier recovery, encapsulated butyric acid can reduce the negative impact of environmental and pathogenic challenges.

Benefits of Butyric Acid

• Antibiotic alternative for broilers and swine
• Cellular signaling to enterocytes¹
• Improves tight junctions in the intestines²
• Increases antioxidant levels to promote healing in the GI tract²
• Improves intestinal development³
• Modulates immune response⁴
• Reduces inflammation⁴

MicroPEARLS™ Technology – Delivering Encapsulated Butyric Acid for Optimum Utilization

A fat matrix encapsulates the butyric acid ensuring the MicroPEARL is not digested; it is the delivery system for the active material. Particles of butyric acid salt are embedded in the MicroPEARLS™ matrix during the manufacturing process. Particles are released in the presence of an aqueous environment, leaving holes to new, unexposed particles.

Liquid enters the MicroPEARL through exterior holes, where it then comes into contact with the other particles of butyric acid. These particles are then released, leaving new holes as liquid contacts them. In the end, the MicroPEARLS look like empty shells. The released material disassociates into butyric acid and calcium. The butyric acid can then be utilized to support efficiency, performance and growth all along the intestinal tract of pigs, broilers, layers and turkeys.

Kemin Triple Check

The Kemin Triple Check product portfolio help establish intestinal integrity and protection. Kemin offers products to CLEAN UP contaminants in feed and water prior to animal exposure, BUILD UP intestinal strength and immunity to reduce leaky gut and KNOCK OUT harmful pathogens for healthier and better performing poultry.

ButiPEARL^® was developed for the BUILD UP category by strengthening the intestinal barrier and immune system to maximize nutrient absorption and inhibit harmful pathogens or toxins.

Resources

References

¹Peng, L., et al. 2009. Butyrate Enhances the Intestinal Barrier by Facilitating Tight Junction Assembly via Activation of AMP-Activated Protein Kinase in Caco-2 Cell Monolayers. J. Nutr. 139:1619-1625.
²Ma, X., et al. 2012. Butyrate promotes the recovering of intestinal wound healing through its positive effect on the tight junctions. J. Anim. Sci. 90 Suppl. 4:266-268.
³Kotunia, A., et al. 2004. Effect of sodium butyrate on the small intestine development in neonatal piglets fed by artificial sow. J. Physiol. Pharmacol. 55 Suppl. 2:59-68.
⁴Guilloteau, P., et al. 2010. From the gut to the peripheral tissues: The multiple effects of butyrate. Nutr. Res. Rev. 23:366-384.

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