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Our Solutions To Negative Mycotoxin Effects In Ruminants

At Kemin, we know that contaminated feed is a prevalent issue within the dairy industry. That’s because feed can be contaminated with mycotoxins — secondary metabolites of fungi (molds) — which has serious consequences for the health of animals and the overall profitability of farms.  

Specifically, mycotoxins within feed can reduce revenues and productivity due to contamination of animal products such as milk. Contamination can also lead to the death of animals, in particular, the death of calves since they are at risk due to their vulnerability. Added to this, the presence of mycotoxins increases overall animal treatment costs. Yet mycotoxins do not only affect animals; contaminated milk also has serious consequences for humans who drink it. In fact, large doses of contaminated milk can result in poisoning, liver damage, and can even be life-threatening.

This is why, at Kemin, we believe in boosting the immune system of ruminants from the start — protecting them from the potentially negative impact of mycotoxins by first and foremost safeguarding their organs. 

Our Solutions To Negative Mycotoxin Effects In Ruminants

For many years, it was believed that ruminants were less susceptible to the negative effects of mycotoxins. It was assumed that most mycotoxins were detoxified in the rumen. However, new research has proven otherwise.

Mycotoxin control is in fact crucial for the health and performance of animals since mycotoxins contaminate all agricultural ingredients, especially silages which are often a prominent source of mycotoxins.

Mycotoxins cause reduced feed intake, alter ruminal fermentation and reduce milk yield, alter reproduction, and cause damage to the liver, kidney, and gastrointestinal system. Mycotoxins such as aflatoxin and T-2 cause immune suppression impacting vaccination efficiency and making ruminants more susceptible to diseases.

It’s important to know that DON, Nivalenol, Ochratoxin, and T-2 are considered to be metabolized in the rumen to less toxic metabolites. However, the emerging mycotoxins, often present in silage, such as Enniatin B, Mycophenolic acid (MPA) and Roquefortine-C remain unchanged and toxic for ruminants. Furthermore, ZEA is metabolized to an even more toxic compound, affecting reproductivity. Aflatoxin is metabolized in the rumen to aflatoxin M1 — a serious concern for human health as it’s excreted in animal milk.

Note that the above is the case in a healthy cow, however, if a cow suffers from SARA (sub-acute rumen acidosis), a highly prevalent disease in cows, the picture changes. DON and nivalenol, as well as the emerging mycotoxins, are not metabolized anymore and remain toxic. Once they enter the intestine, some of them — MPA, ZEA and NIV for example — have very cytotoxic effects and compromise intestinal integrity, meaning the ruminant’s predisposition for enteric problems and diseases.

Unfortunately, mycotoxins do not only affect ruminants, they also affect human health — in fact, some mycotoxins and their metabolites are also excreted in milk, especially aflatoxin M1 (AFM1), which is carcinogenic.

What is more, is a general underestimation regarding the effects of mycotoxins in ruminants. At Kemin, our research shows that this is because of:

  • Incorrect sampling due to the occurrence of hotspots;
  • Masked mycotoxins — mycotoxins bound to components in feed, such as sugars, escape analyzes but remain toxic to the animal;
  • Emerging mycotoxins are not routinely analyzed, especially those present in silages.

Learn more about Mycotoxin Management in our brochure

Protecting ruminants from the adverse effects of mycotoxin ingestion in contaminated feed is our priority. That’s why, at Kemin, we provide complete scientific support through innovative services and comprehensive research. This is done through our unique Mycotoxin Management Toolbox — the product of over a decade of industry experience and research.

Role of TOXFIN - Mycotoxin Management Toolbox

Kemin’s complete Mycotoxin Management Toolbox 

As part of our toolbox, we guide animal nutritionists and health specialists on the use of raw materials to ensure high-quality and safe feed formulations — leading to healthier ruminants and increased farm profitability.

Our Mycotoxin Management Toolbox focuses on the following 3 activities to support you:

  1. Mitigating Risk - our Customer Laboratory Services (CLS) helps you with extensive mycotoxin Feed Analyses for your poultry;
  2. Protecting the Animal - our TOXFIN® range of products supports you in the mitigation of mycotoxins in poultry;
  3. Enabling Feed Control - our Myco CURB® is a premier product in pig feed preservation and mold control in feed. 

1. Mitigating Risk

Kemin’s Customer Laboratory Services (CLS) helps you in lessening the risks of mycotoxins in ruminants and includes:

  • On-farm evaluation of mycotoxin raw materials:
    • Fast testing;
    • Quick and effective raw material screening.
  • Profound finished feed laboratory services:
    • Various mycotoxin evaluation;
    • Variety of matrices;
    • Specific and precise measurements;
    • Full mycotoxin risk assessment.
  • Prediction of requirements of mycotoxin binder;
  • Mycotoxins today:
    • Thousands of mycotoxin analyses;
    • Regional mycotoxin data;
    • Seasonal mycotoxin data;
    • Risk assessment;
    • Benchmarking.

2. Kemin’s TOXFIN Range to address mycotoxins

Every single day new insights on mycotoxins arise. This means we need to be on top of our game to adapt these insights into concrete solutions to guide you in reducing the effects of mycotoxins in ruminants.

Download our brochure for more detailed information

Kemin’s TOXFIN range offers various unique solutions to reduce the bioavailability of mycotoxins and  their negative effects, aiding the production of safe feed:

  • TOXFIN CARE - Kemin’s TOXFIN CARE is the best protection for ruminants with the following key benefits. TOXFIN CARE: 
    • Offers thorough protection against mycotoxins using an all-in-one strategy;
    • Reduces bioavailability of mycotoxins with a unique adsorbent blend ((e.g. bentonite (1m558) fulfilling European Regulation 1060/2013 as an aflatoxin B1 binder);
    • Prevents oxidative stress using plants extracts;
    • Supports and protects the liver through plants extracts;
    • Modulates the immune system using a unique algae-derived beta-glucan.
  • TOXFIN Dry - TOXFIN Dry offers cost-effective protection with a Synergistic Binder, for the production of safe milk in ruminants. TOXFIN Dry is a carefully selected blend of unique activated adsorbents (e.g. bentonite (1m558) fulfilling the European Regulation 1060/2013 as an aflatoxin B1 binder) that binds the relevant mycotoxins along the gastrointestinal tract — reducing mycotoxin bioavailability and promoting their excretion from the ruminant’s body.
  • TOXFIN XL - TOXFIN XL offers effective protection with a specialised synergistic binder, for reproduction issues caused by ZEA in ruminants. TOXFIN XL is a carefully selected blend of unique activated adsorbents (e.g. bentonite (1m558) fulfilling the European Regulation 1060/2013 as an aflatoxin B1 binder) fortified with specifically activated argillaceous minerals that bind all relevant mycotoxins along the gastrointestinal tract. This reduces mycotoxin bioavailability and promotes their excretion from the animal’s body.
TOXFIN Care - Product Information - EU
TOXFIN Dry - Product Information - EU
TOXFIN XL - Product Information - EU

3. Myco CURB

Myco CURB is our superb mold inhibitor that preserves grains and prevents them from mold contamination. Stabilization of the grains and oilseeds with Myco CURB ensures optimal nutritive value in the feed and provides a natural insurance system.

The following key benefits of Myco CURB are that it:

  • Inhibits mold — Myco CURB preserves feed and raw materials from mold contamination, and thus mycotoxin production;
  • Drastically reduces and controls total mold counts and mites;
  • Contributes significantly to the success of Good Storage Practices, minimizing the risk of grain deterioration and adjusting the protection following risk factors;
  • Provides merchants and farmers with an economical alternative processing solution at harvest for cereals and oilseeds. It is possible to harvest grain at the optimum ripening time, hence providing increased flexibility;
  • Ensures treated grain is safely stored and has an extended shelf-life after further processing. If the cereal is rolled, the appearance is ideal and robust for coarsely mixed diets.
Myco CURB - Product Information - EU

Our Kemin-created Customer Laboratory Services (CLS) lets you maintain your feed quality and safety through Routine Mycotoxin Screening of Feed Samples. We constantly screen thousands of feed and raw material samples to generate a huge database, which also shows regional and seasonal mycotoxin contaminations. Moreover, all data are gathered in regional surveys. Additionally, after a thorough screening, a tailor-made mycotoxin prevention program is drawn up for you. 

Read more here

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