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Animal Nutrition & Health

CLOSTAT® – Gut Health Probiotic for Pigs and Poultry

CLOSTAT® is Kemin’s most trusted probiotic solution, supporting gut health and optimising animal performance for over two decades.

CLOSTAT contains patented Bacillus valezensis  PB6 (ATCC PTA-6737) that helps reduce reliance on antibiotics and promotes a healthy microbiome. From sows to fattening pigs and layers to broilers, CLOSTAT delivers consistent results across species and production stages, helping to improve productivity, lower costs, and support sustainable farming for pig and poultry producers.

KAE PRODUCT LOGO Button_CLOSTAT (white)

Scientifically Proven Benefits

  • Naturally supports gut health, reducing reliance on antibiotics.
  • Encourages the recovery of gut health following antibiotic treatments.
  • Mitigates common digestive issues such as dysbiosis, wet litter, and diarrhoea.
  • Promotes the growth of beneficial bacteria such as Lactobacillus and Bifidobacteria.
  • Helps manage enteritis and Clostridium-related symptoms.

How CLOSTAT Works: The Science Behind the Strain

CLOSTAT delivers targeted probiotic action through a patented Bacillus valezensis strain, supporting gut health and resilience under commercial production conditions.

  • Bacillus valezensis  PB6: A patented spore-forming strain that reaches the intestine alive
  • Microbiome Modulation: Encourages growth of beneficial bacteria (Lactobacillus, Bifidobacteria)
  • Pathogen Control: Shown to suppress Clostridium spp. and reduce enteric inflammation
  • Stable Formulation: Withstands feed processing and maintains viability under commercial conditions

Targeted Gut Health Support for Every Pig Stage

Raising pigs presents unique challenges at every stage of production. CLOSTAT is designed to support intestinal health and optimise performance from farrow to finish, ensuring strong, healthy pigs and reducing the need for antibiotics.

  • Sows: Supports reproductive performance and resilience by stabilising the gut microbiome—improving feed efficiency, litter uniformity, and sow well-being.
  • Piglets: Reduces weaning stress and enteric infections, enhancing nutrient absorption and minimising dysbiosis for stronger, more uniform piglets.
  • Fattening Pigs: Enhances growth performance and feed efficiency through microbiome stabilisation, offering a sustainable solution to common gut health challenges.
Eco pig farm in the field in Denmark

A Probiotic Solution for Poultry Health and Performance

Poultry face a range of enteric health challenges throughout production. CLOSTAT supports intestinal stability and performance in broilers and layers—reducing reliance on antibiotic growth promoters and improving overall flock outcomes.

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  • During Stress Events: Stabilises the microbiome during dietary transitions, heat stress, or vaccinations to maintain gut integrity and performance.
  • Enteric Health: Mitigates dysbiosis, wet litter, and Clostridium-related enteritis, supporting healthier flocks and better litter quality.
  • Performance Outcomes: Enhances growth and uniformity in broilers and improves eggshell consistency in layers through targeted probiotic action.

Sustainable Pig and Poultry Production

As the industry moves away from routine antibiotic use, CLOSTAT offers a reliable and sustainable alternative. Life Cycle Assessment data shows that improved gut health with CLOSTAT leads to:

  • Lower feed consumption through better nutrient utilisation
  • Reduced need for antibiotic treatments
  • Lower environmental footprint via improved efficiency
  • Support for responsible production aligned with regulatory and market demands

Proven Probiotic Performance for Pigs and Poultry Since 2004

Recognised for its innovation and efficacy, CLOSTAT has earned multiple industry accolades, including the Animal Pharm Best New Product Award (2005), the World Poultry Innovation Award (2006), and the Asian Agribiz Product of the Year Award (2018). 

Kemin is your reliable service partner to tackle persistent and complex challenges in animal nutrition and health throughout the continually evolving feed to food chain.

Resources

Intestinal Microbiome of Broilers - PDF Thumbnail

The Intestinal Microbiome of Broilers

Download

CLOSTAT Leaflet for Vets thumbnail

Leaflet for Veterinarians

Download

CLOSTAT Leaflet for Feed Mill Operators thumbnail

Leaflet for Feed Mill Operators

Download

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Animal Nutrition & Health

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