CLOSTAT™ for GUT Health

Intestinal health issues in poultry and livestock are of constant concern to producers around the world. CLOSTAT™ is a patented direct-fed microbial that supports intestinal health by maintaining a balanced microbiota. It has been proven to help develop a natural defense mechanism against Clostridium perfringens.

The Science Behind Kemin Gut Health Solutions

We isolated an active microbial from the intestinal tract of healthy chickens to develop a unique strain of Bacillus subtilis, PB6.

CLOSTAT™ produces lipopeptides (surfactants) in the gastrointestinal tract that have inhibitory activity against pathogenic strains of Clostridium perfringens. These surfactants also have efficient anti-inflammatory properties.

CLOSTAT™ is not species specific, meaning that it can be used in all animal species. In Asia, CLOSTAT™ is generally registered for poultry and swine.


Features of CLOSTAT™

  • Stable in feed and premixes
  • Heat stable upon pelleting
  • Compatible with nearly all organic acids
  • Compatible with nearly all anticoccidials

Benefits of Using CLOSTAT™

  • Production of surfactin with specific activity against pathogenic strains of Clostridium perfringens
  • Prevention of necrotic enteritis, bacterial enteritis, and maintenance of a balanced microbiota
  • Production of flocks and livestock in an environment with reduced antibiotic use
  • Reduction in medication application due to improved gut health management
  • Improved profitability through reduced mortalities, improved litter quality and performance, and reduced rejections at slaughterhouse


Chick looking at the mirror of it being a chicken, saying start early, finish strong

CLOSTAT is an active microbial effective against pathogenic strains of Clostridium perfringens, which serves as a natural solution for the responsible use of antibiotics.

CLOSTAT™ is compatible with common feed additives and most coccidiostats used in the feed industry and is heat stable under normal commercial pelleting conditions. 

Exceptional customer service with best-in-class technical, laboratory and customer support from our dedicated teams and well-equipped laboratory.

  • Clostridium Test Kits
  • Farm and facility audits to identify gut health issues
  • Feed and premix analysis to ensure recovery of CLOSTAT™


Range of variant CLOSTAT product available in 5, 20 & 25kg packaging
Range of Products

*Certain packaging sizes may not be available in certain regions

Certain statements may not be applicable in all geographical regions. Product labeling and associated claims may differ based upon government requirements. All claims are supported by scientific and field data.



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