BetaVia™ Nature's Immune and Gut Promoter

BetaVia™ is a naturally sourced, algae-based beta glucan dietary ingredient that supports both the immune and gastrointestinal systems, providing benefits for immune, digestive, and respiratory health.

This natural and clinically studied ingredient is sustainably produced from a proprietary strain of Eugena gracilis¹ algae. BetaVia is a rich source of beta 1,3 glucans available in diverse product forms suitable for different applications including water dispersible.

Science-Backed Benefits^2-24

• Postbiotic for immune and gastrointestinal health
• Supports a healthy immune system
• Encourages optimal immune function
• Supports/maintains respiratory tract health
• Supports/maintains digestive tract health
• Supports/maintains gastrointestinal comfort
• May protect against oxidative stress

BetaVia’s proposed Mechanism of Action : a Triple-Action Protection^10,11,25,26

• Priming key immune cells
• Protecting intestinal barrier integrity
• Shaping the microbiome

How Does BetaVia work in the gut?

BetaVia is a postbiotic for your gut. By interacting with gut microbiota, BetaVia can serve as an energy source to promote the growth of “good” bacteria helping to shape the microbiome. Finally, BetaVia can interact with and primate innate immune cells which impacts your gastrointestinal health since a large portion of the immune system is located within your gut.²⁷

How Does BetaVia work for immune health?

Check out our video below to learn how BetaVia works for your immune health.

Formulation and Innovation to Boost Immune and Gut Products

Formulate BetaVia into a variety of finished products, including functional foods, beverages, and supplements. Kemin’s experience in prototyping products with BetaVia can help speed up your development of these products. Complement with other immune support ingredients for a competitive advantage and differentiation in the market. In some formulations, slight flavors or aromas are easily masked. 

Applications include: 

• Tablets and capsules
• Powders and stick packs
• Beverages, syrups and liquids
• Bars and baked goods
• Hard candy and lozenges
• Gummies and chews
• Softgels
• Effervescents
• Chocolate

BetaVia ingredients are natural and safe immune and gut supporting ingredients with an established regulatory status on a global basis.

GRAS, Kosher, Halal, Vegetarian, Gluten free, Allergen free, GMO-free, naturally and sustainably-sourced

Ready To Set Your Product Apart With BetaVia?

Complete the form and a Kemin representative will get in touch soon with details on our euglena gracilis beta glucan, BetaVia.

These statements have not been evaluated by the US Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

The information on this webpage is a business-to-business information and not intended for the final consumer. Certain statements may not be applicable in all geographical regions. Product labeling and associated claims differs based upon government requirements and country or region specific information should also be considered when labeling or advertising to final consumers.

This web page and its associated brochures and other documents do not constitute or provide scientific or medical advice, diagnosis, or treatment and are distributed without warranty of any kind, either expressly or implied. This web page, its title or contents and associated brochures and other documents do not in any way make recommendations for health or marketing claims by the reader. Country and region specific regulations should be considered in this regard. Each claim or statement about the effectiveness of Kemin products and/or each claim or statement comparing the effectiveness of Kemin products to the effectiveness of other products is expressly limited to the United States, unless otherwise disclosed on the Kemin websites.

References

1. Euglena gracilis ATCC PTA-123017
2. Salminen, et al. Nat rev Gastroenterol Hepatol (2022). https://www.nature.com/articles/s41575-021-00440-6
3. Evans, M., et al., Effect of a Euglena gracilis Fermentate on Immune Function in Healthy, Active Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.  Nutrients, 2019, 11(12), 2926
4. Kemin, BetaVia Complete can prime key cells in the innate immune system. KHTL-017-150.
5. KHTL-017-162 BetaVia Pure Can Prime Key Cell sin the Innate Immune system. KHTL-017-150.
6. KHTL-017-160 Paramylon Improves Antioxidant Status and Metabolic Health-TL-20-18529
7. KHTL-017-149 Characteristics and Prebiotic like Properties of BetaVia Complete
8. Kemin, Characteristics and prebiotic like properties of BetaVia Complete. KHTL-017-149.
9. Bhattad T, Koradiya A, Prakash G. Prebiotic activity of paramylon isolated from heterotrophically grown Euglena gracilis. Heliyon. 2022 Aug 27;7 (9): e07884. doi: 10.1016/j.heliyon.2022.e07884
10. Russo, R., et al. “Euglena gracilis paramylon activates human lymphocytes by upregulating pro-inflammatory factors.” Food Science & Nutrition 5.2 (2017): 205-214
11. Kondo, Y., et al. "Cytokine-related immunopotentiating activities of Paramylon, a β-(1→ 3)-D-glucan from Euglena gracilis." Journal of Pharmacobio-dynamics 15.11 (1992): 617-621.
12. Kankkunen, P., et al. "(1, 3)-β-Glucans activate both dectin-1 and NLRP3 inflammasome in human macrophages." The Journal of Immunology 184.11 (2010): 6335-6342
13. Brown, G.D., and Siamon G. Immune recognition: A new receptor for [beta]-glucans." Nature 413.6851 (2001): 36.
14. Brown, G.D., et al. "Dectin-1 is a major β-glucan receptor on macrophages. Journal of Experimental Medicine 196.3 (2002): 407-412.
15. Brown, G.D., et al. Dectin-1 mediates the biological effects of β-glucans." Journal of Experimental medicine 197.9 (2003): 1119-1124.
16. Goodridge, H.S. et al. "β‐glucan recognition by the innate immune system. Immunological reviews 230.1 (2009): 38-50.
17. KEMIN internal document: SD-18-00083
18. Ishibashi, Ken-ichi, et al. “Effects of Euglena gracilis EOD-1 ingestion on salivary IgA reactivity and health-related quality of life in humans.” Nutrients 11.5 (2019): 1144.
19. Nakashima, Ayaka, et al. “The alga Euglena gracilis stimulates Faecalibacterium in the gut and contributes to increased defecation.” Scientific reports 11.1 (2021): 1-8.
20. Nakashima, Ayaka, et al. “Effects of Euglena gracilis Intake on Mood and Autonomic Activity under Mental Workload, and Subjective Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Trial.” Nutrients 12.11 (2020): 3243.
21. Kawano, Takanori, et al. “Effect of Food Containing Paramylon Derived from Euglena gracilis EOD-1 on Fatigue in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Trail.” Nutrients 12.10 (2020): 3098.
22. SD-17-00243 Kemin Internal Document (Effect of 50%BG on the immune and intestinal health status of weaned piglets)
23. SD-9-21271 Kemin Internal Document (Effect of 50% BG on IgA in piglet feces)
24. TD-17-0322 Kemin Internal Document (Effect of 50% and 95% BG on gut and systemic immunity in mice)
25.  KHTL-017-159 BetaVia Complete Supports Gut Health after Induced Colitis in Mice
26.  Kemin Proprietary Data TD-20-6867
27. Vighi, G., Marcucci, F., Sensi, L., Di Cara, G., & Frati, F. (2008). Allergy and the gastrointestinal system. Clinical and experimental immunology, 153 Suppl 1(Suppl 1), 3–6. https://doi.org/10.1111/j.1365-2249.2008.03713.x