CORYVAC™

Treating Coryza caused by Avibacterium paragallinarum

Infectious Coryza (IC) is an avian disease affecting the upper respiratory tract of poultry, caused by a gram negative non-motile bacterium called Avibacterium paragallinarum, which is grouped into different serogroups: A, B, C.¹

The clinical signs in the acute phase include:

1. Nasal discharge
2. Facial swelling
3. Lacrimation

In the chronic phase birds become carriers for life, even without clinical signs, therefore, the economic impact can be associated with a decrease in egg production (10%-40%), added treatment costs and compromised egg quality. ^2,3,4,5

The multiple serovars of Avibacterium paragallinarum and the absence of cross-protection among them are suspected to be the cause of frequent failures of vaccination programs.^2,3

CORYVAC™ Product Details

Withdrawal

Zero days. 

Considerations

• The vaccine should not be used if chickens are diseased or immunosuppressed.
• Do not mix with any other veterinary medicinal product.
• No side-effect has been observed during the rearing period following administration of double the recommended dose of vaccine.
• The safety of the veterinary medicinal product has not been established during lay.
• Vaccine bottles shall be shaken well before use.
• Use sterile injection equipment.

Dosage

The vaccine dose (0.5 mL/bird) should be administered subcutaneously in the lower part of the neck or intramuscularly in the thigh or breast muscles.

Administration

Before use, the vaccine should be shaken well to ensure proper mixing. Sterile injection equipment should be used to avoid contamination.

• Subcutaneous injection: in the lower part of the neck. The needle should be inserted just under the skin in a direction away from the head and in a straight line with the neck.
• Intramuscular injection: in the breast muscles by inserting the needle with a 45° angle to avoid intraperitoneal injection.

Storage Precautions

• Store and transport refrigerated (+2°C to +8°C). 
• Do not freeze.
• Store in a dry place protected from direct sunlight.
• Do not use this product after the expiry date.
• Shelf life after first opening the bottle: 3 hours.

Presentation

CORYVAC™ is packed and presented in 500 mL (1000 doses) polyethylene terephthalate (PET) bottles.

References

1. Anjaneya S.D, Singh K, Dhama V, Gowthaman Chawak M.M. Pathogenicity study of field isolates of Avibacterium paragallinarum in experimentally infected birds. Indian J. Vet. Pathol. 2013.

2. Dungu, B., Brett, B., et al., Study on the efficacy and safety of different antigens and oil formulations of infectious coryza vaccines containing an NAD-independent strain of Avibacterium paragallinarum. Onderstepoort J.Vet. Res.

1. Chukiatsiri, K., Sasipreeyajan, J., et al., Efficacy of autogenous killed vaccine of Avibacterium paragallinarum. Avian Dis. 2009.

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