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BetaVia™ Nature's Immune and Gut Promoter

BetaVia™ is a naturally sourced, algae-based beta glucan dietary ingredient that uniquely supports both the immune and gastrointestinal systems. Derived from a proprietary strain of Euglena gracilis algae1, BetaVia offers diverse product forms suitable for various applications, including water dispersible options.

Science-Backed Benefits2-24

BetaVia serves as a postbiotic, supporting both immune and gastrointestinal health. It aids in maintaining a robust immune system and a healthy respiratory tract while promoting digestive health. Additionally, BetaVia offers potential protection against oxidative stress, further enhancing its role in overall health support.

Why Choose BetaVia?

  1. Label Friendly Beta Glucan: Crafted from non-GMO algae adhering to strict quality standards
  2. Purity: BetaVia is available in two concentrations, >50% beta glucan and >95% beta glucan - the purest beta glucan available
  3. Clinical Evidence: Supported by clinical studies showcasing dual benefits for immune and gastrointestinal (GI) health

Clinical Research Highlights

BetaVia employs a triple-action protection mechanism3, involving priming key immune cells, shaping the microbiome, and safeguarding intestinal barrier integrity. This approach enhances immune health by interacting with innate immune cells crucial for overall immune function, particularly vital given the significant immune system presence in the gut.

In a 90-day double-blind, placebo-controlled study3, BetaVia demonstrated effectiveness in reducing the likelihood and severity of upper respiratory tract infection (URTI) symptoms, yielding significant results compared to the placebo group. Participants experienced 70% fewer URTI symptoms, with a 3.3-day decrease in sick days and 10 fewer days with URTI symptoms during the trial period.

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Furthermore, BetaVia supports gut health by acting as a postbiotic, interacting with gut microbiota to promote the growth of beneficial bacteria and priming key immune cells for optimal gastrointestinal health.27 This contributes to a healthy gut barrier, allowing essential nutrients to enter while preventing harmful bacteria and toxins from permeating. Studies have shown improved gastrointestinal comfort, modulation of key markers of intestinal barrier integrity, shaping of the microbiome, and enhanced ease of stool passage, underscoring BetaVia's ability to improve gut health by fortifying the intestinal barrier and influencing the microbiome.29-31

Patented Production Process

BetaVia's efficient fermentation process ensures quality and consistency, adhering to current Good Manufacturing Practices (cGMPs), setting it apart from other immune and gut health ingredients.

Formulation Opportunities

BetaVia Features

  • Clinically studied
  • Natural, algae-based source of beta 1,3 glucan
  • Free from added excipients
  • Patented and efficient fermentation process
  • Manufactured with meticulous attention to quality in a GMP-certified facility
  • Adaptable to various formulations, offering versatility across multiple formats
  • Water dispersible formats available
  • GRAS-certified and suitable for daily consumption
  • Non-GMO, Kosher, Halal, and vegan-friendly      
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BetaVia serves as a stable and highly adaptable ingredient, seamlessly integrating into a wide array of formulations. Our Customer Laboratory Service team specializes in leveraging our ingredients to assist in bringing your products to life. Choose BetaVia for a natural, efficacious, and scientifically supported solution to enhance your immune and gut health formulations.

Resources

BetaVia™: Unlocking Every Body's Natural Defenses

Download

Partners for Better Health: The Gut and the Immune System

Download

Make the Connection: The Link Between Sleep and Immune Health

Download

Beta-Glucans for Immune Support: Algae vs. Traditional Sources

Download

Navigating the Trends and Innovations in Gut Health

Download

Digestive Aging™: The Quest to Keep the Gut Young at Heart 

Download

Navigating Women's Health Paradoxes

Download

Ready to add BetaVia to your formulation?

Request more information below.

These statements have not been evaluated by the US Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

The information on this webpage is a business-to-business information and not intended for the final consumer. Certain statements may not be applicable in all geographical regions. Product labeling and associated claims differs based upon government requirements and country or region specific information should also be considered when labeling or advertising to final consumers.

This web page and its associated brochures and other documents do not constitute or provide scientific or medical advice, diagnosis, or treatment and are distributed without warranty of any kind, either expressly or implied. This web page, its title or contents and associated brochures and other documents do not in any way make recommendations for health or marketing claims by the reader. Country and region specific regulations should be considered in this regard. Each claim or statement about the effectiveness of Kemin products and/or each claim or statement comparing the effectiveness of Kemin products to the effectiveness of other products is expressly limited to the United States, unless otherwise disclosed on the Kemin websites.

References

  1. Euglena gracilis ATCC PTA-123017
  2. Salminen, et al. Nat rev Gastroenterol Hepatol (2022). https://www.nature.com/articles/s41575-021-00440-6
  3. Evans, M., et al., Effect of a Euglena gracilis Fermentate on Immune Function in Healthy, Active Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.  Nutrients, 2019, 11(12), 2926
  4. Kemin, BetaVia Complete can prime key cells in the innate immune system. KHTL-017-150.
  5. KHTL-017-162 BetaVia Pure Can Prime Key Cell sin the Innate Immune system. KHTL-017-150.
  6. KHTL-017-160 Paramylon Improves Antioxidant Status and Metabolic Health-TL-20-18529
  7. KHTL-017-149 Characteristics and Prebiotic like Properties of BetaVia Complete
  8. Kemin, Characteristics and prebiotic like properties of BetaVia Complete. KHTL-017-149.
  9. Bhattad T, Koradiya A, Prakash G. Prebiotic activity of paramylon isolated from heterotrophically grown Euglena gracilis. Heliyon. 2022 Aug 27;7 (9): e07884. doi: 10.1016/j.heliyon.2022.e07884
  10. Russo, R., et al. “Euglena gracilis paramylon activates human lymphocytes by upregulating pro-inflammatory factors.” Food Science & Nutrition 5.2 (2017): 205-214
  11. Kondo, Y., et al. "Cytokine-related immunopotentiating activities of Paramylon, a β-(1→ 3)-D-glucan from Euglena gracilis." Journal of Pharmacobio-dynamics 15.11 (1992): 617-621.
  12. Kankkunen, P., et al. "(1, 3)-β-Glucans activate both dectin-1 and NLRP3 inflammasome in human macrophages." The Journal of Immunology 184.11 (2010): 6335-6342
  13. Brown, G.D., and Siamon G. Immune recognition: A new receptor for [beta]-glucans." Nature 413.6851 (2001): 36.
  14. Brown, G.D., et al. "Dectin-1 is a major β-glucan receptor on macrophages. Journal of Experimental Medicine 196.3 (2002): 407-412.
  15. Brown, G.D., et al. Dectin-1 mediates the biological effects of β-glucans." Journal of Experimental medicine 197.9 (2003): 1119-1124.
  16. Goodridge, H.S. et al. "β‐glucan recognition by the innate immune system. Immunological reviews 230.1 (2009): 38-50.
  17. KEMIN internal document: SD-18-00083
  18. Ishibashi, Ken-ichi, et al. “Effects of Euglena gracilis EOD-1 ingestion on salivary IgA reactivity and health-related quality of life in humans.” Nutrients 11.5 (2019): 1144.
  19. Nakashima, Ayaka, et al. “The alga Euglena gracilis stimulates Faecalibacterium in the gut and contributes to increased defecation.” Scientific reports 11.1 (2021): 1-8.
  20. Nakashima, Ayaka, et al. “Effects of Euglena gracilis Intake on Mood and Autonomic Activity under Mental Workload, and Subjective Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Trial.” Nutrients 12.11 (2020): 3243.
  21. Kawano, Takanori, et al. “Effect of Food Containing Paramylon Derived from Euglena gracilis EOD-1 on Fatigue in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Trail.” Nutrients 12.10 (2020): 3098.
  22. SD-17-00243 Kemin Internal Document (Effect of 50%BG on the immune and intestinal health status of weaned piglets)
  23. SD-9-21271 Kemin Internal Document (Effect of 50% BG on IgA in piglet feces)
  24. TD-17-0322 Kemin Internal Document (Effect of 50% and 95% BG on gut and systemic immunity in mice)
  25.  KHTL-017-159 BetaVia Complete Supports Gut Health after Induced Colitis in Mice
  26.  Kemin Proprietary Data TD-20-6867
  27. Vighi, G., Marcucci, F., Sensi, L., Di Cara, G., & Frati, F. (2008). Allergy and the gastrointestinal system. Clinical and experimental immunology, 153 Suppl 1(Suppl 1), 3–6. https://doi.org/10.1111/j.1365-2249.2008.03713.x
  28. Patents granted a patent on beta 1,3 glucans for modulating immune function (US Patent 10,912,794).  This new patent joins a previously issued patent, US 9574217, on the production of immune modulation using algae from a proprietary strain of Euglena gracilis ATCC PTA-123017.
  29. KHTLA-017-181 BetaViaTM helps to Maintain Health and Promote Gut Health by Supporting Intestinal Barrier Integrity
  30. KHTLA-017-180 BetaViaTM A Natural New-Generation Postbiotic that works as both an Immune Gut Health Promoter
  31. KHTLA-017-148 (TL-20-18591) Characteristics and Prebiotic like properties of BetaVia Complete 
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