Introducing Macu-LZ™ Lutein & Zeaxanthin Isomers for Comprehensive Nutraceutical Solutions

At Kemin, we're compelled by curiosity to explore the frontiers of health and wellness, driven by a passion to uncover solutions that truly make a difference. It's this relentless pursuit of knowledge and innovation that has led us to develop Macu-LZ™, a carotenoid formulation designed to target the intricate connections between eye, brain, and skin health.

Proven Bioavailability and Formulation Versatility

At the core of Macu-LZ lies its commitment to efficacy and ease of use. Leveraging DSM’s Actilease^® microencapsulation technology, Macu-LZ ensures proven bioavailability, stability, and minimal extrusion losses allowing formulating with it seamless.¹ Available in oil suspensions and beadlets, allowing it to integrate into various supplement forms, including capsules, tablets, gummies, chews, and beverages.

Tailored Dosage for Optimal Efficacy

With recommended doses ranging from 12 to 24 mg, Macu-LZ offers flexibility to cater to diverse health needs. Whether aiming for 10 mg lutein and 2 mg zeaxanthin isomers or 20 mg lutein and 4 mg zeaxanthin isomers, Macu-LZ ensures consistent and reliable delivery of benefits.

State-of-the-Art Beadlet Stability

Macu-LZ sets a new standard in stability and performance with its state-of-the-art beadlet technology. Through DSM’s Actilease^® innovation, Macu-LZ minimizes losses during tablet manufacturing, reducing the need for overages. Moreover, our dedicated Customer Laboratory Services (CLS) team provides comprehensive support to ensure product formulations align with label claims.

Science-Backed Benefits^2-10

The benefits of lutein and zeaxanthin isomers extend beyond eye health. Macu-LZ's triple formula addresses not only vision quality but also cognitive function, stress response, and sleep quality. By elevating levels of Brain-Derived Neurotrophic Factor (BDNF), Macu-LZ promotes neuroplasticity and cognitive well-being. Additionally, its skin-enhancing properties offer protection and radiance, contributing to a vibrant complexion.

Supporting Farming Communities

Behind every Macu-LZ product lies a commitment to sustainability and community empowerment. Sourced from marigold flowers cultivated by farmers in India, Macu-LZ supports local economies and fosters a better quality of life for farming communities. Through our partnership, we ensure fair practices and contribute to educational opportunities, creating a ripple effect of positive change.

Features that Prioritize Well-being

Macu-LZ stands as a beacon of safety, quality, and transparency. With designations such as Self-Affirmed Generally Recognized As Safe (GRAS), Plant-Based, Non-GMO, Vegetarian, and Gluten-Free, Macu-LZ aligns with diverse dietary preferences and ethical considerations.

Seed to Product Excellence

Through meticulous control from seed to product, Macu-LZ guarantees transparency and traceability, ensuring peace of mind for both manufacturers and consumers alike. With certifications for Kosher and Halal standards, Macu-LZ upholds inclusivity and integrity every step of the way.

At its core, Macu-LZ is not only a supplement – it's a reflection of Kemin's steadfast dedication to discovering the full power of nature, motivated by curiosity and guided by a passion for wellness. Join us on this journey towards a healthier, happier future.

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Actilease® is a Registered Trademark of DSM Nutritional Products Ltd.

These statements have not been evaluated by the US Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

The information on this webpage is a business-to-business information and not intended for the final consumer. Certain statements may not be applicable in all geographical regions. Product labeling and associated claims differs based upon government requirements and country or region specific information should also be considered when labeling or advertising to final consumers.

This web page and its associated brochures and other documents do not constitute or provide scientific or medical advice, diagnosis, or treatment and are distributed without warranty of any kind, either expressly or implied. This web page, its title or contents and associated brochures and other documents do not in any way make recommendations for health or marketing claims by the reader. Country and region specific regulations should be considered in this regard. Each claim or statement about the effectiveness of Kemin products and/or each claim or statement comparing the effectiveness of Kemin products to the effectiveness of other products is expressly limited to the United States, unless otherwise disclosed on the Kemin websites.

Refernces: 

1. Evans et. al., Eur J Nutr. 2013 Jun;52(4): 1381-91.
   
2. uturu, V., Bowman, J. P., Stringham, N. T., & Stringhan, J. M. (2016). Bioavailability of lutein/zeaxanthin isomers and macular pigment optical density response to macular carotenoid supplementation: A randomized double-blind placebo-controlled study. New Front. Ophthalmol, 2, 140-145.
3. Juturu, V., Bowman, J. P., & Deshpande, J. (2016). Overall skin tone and skin-lightening-improving effects with oral supplementation of lutein and zeaxanthin isomers: a double-blind, placebo-controlled clinical trial. Clinical, cosmetic and investigational dermatology, 9, 325.
4. Stringham, J. M., O’Brien, K. J., & Stringham, N. T. (2016). Macular carotenoid supplementation improves disability glare performance and dynamics of photostress recovery. Eye and Vision, 3(1), 30.
5. Stringham, J. M., & Stringham, N. T. (2016). Serum and retinal responses to three different doses of macular carotenoids over 12 weeks of supplementation. Experimental eye research, 151, 1-8.
6. Stringham, J. M., O'Brien, K. J., & Stringham, N. T. (2017). Contrast sensitivity and lateral inhibition are enhanced with macular carotenoid supplementation. Investigative ophthalmology & visual science, 58(4), 2291-2295.
7. Stringham, J. M., Stringham, N. T., & O’Brien, K. J. (2017). Macular carotenoid supplementation improves visual performance, sleep quality, and adverse physical symptoms in those with high screen time exposure. Foods, 6(7), 47.
8. Culver, M. F., Bowman, J., & Juturu, V. (2018). Lutein and Zeaxanthin Isomers Effect on Sleep Quality: A Randomized Placebo-Controlled Trial.
9. Stringham, N. T., Holmes, P. V., & Stringham, J. M. (2018). Supplementation with macular carotenoids reduces psychological stress, serum cortisol, and sub-optimal symptoms of physical and emotional health in young adults. Nutritional neuroscience, 21(4), 286-296.
10. Stringham, N. T., Holmes, P. V., & Stringham, J. M. (2019). Effects of macular xanthophyll supplementation on brain-derived neurotrophic factor, pro-inflammatory cytokines, and cognitive performance. Physiology & behavior, 211, 112650