Product Overview
CORYVAC™ is an inactivated trivalent vaccine against Infectious Coryza caused by Avibacterium paragallinarum serogroups A, B & C.
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CORYVAC™
CORYVAC™ is an inactivated trivalent vaccine against Infectious Coryza caused by Avibacterium paragallinarum serogroups A, B & C.
Chickens.
Infectious Coryza (IC) is an avian disease affecting the upper respiratory tract of poultry, caused by a gram negative non-motile bacterium called Avibacterium paragallinarum, which is grouped into different serogroups: A, B, C.1
The clinical signs in the acute phase include: 1) nasal discharge; 2) facial swelling; and 3) lacrimation. In the chronic phase birds become carriers for life, even without clinical signs, therefore, the economic impact can be associated with a decrease in egg production (10%-40%), added treatment costs and compromised egg quality.2,3,4,5
Infectious Coryza can also trigger secondary infection with other major pathogens, such as Mycoplasma gallisepticum, M. synoviae, Escherichia coli, Pasteurella multocida, and viral pathogens like infectious bronchitis virus (IBV), infectious laryngotracheitis virus (ILT) and fowl pox virus (FPV).1,6,7,8
The multiple serovars of Avibacterium paragallinarum and the absence of cross-protection among them are suspected to be the cause of frequent failures of vaccination programs.9,10
For the immunization of chickens to protect against the clinical signs and mortality associated with Infectious Coryza.
Birds can be vaccinated from the age of 8 to 16 weeks onwards, as per advice from your poultry veterinarian. A second dose should be given 3-4 weeks later, at least two weeks before the onset of lay.
Zero days.
The vaccine dose (0.5 mL/bird) should be administered subcutaneously in the lower part of the neck or intramuscularly in the thigh or breast muscles.
Before use, the vaccine should be shaken well to ensure proper mixing. Sterile injection equipment should be used to avoid contamination.
CORYVAC™ is packed and presented in 500 mL (1000 doses) polyethylene terephthalate (PET) bottles.
References
1. Anjaneya S.D, Singh K, Dhama V, Gowthaman Chawak M.M. Pathogenicity study of field isolates of Avibacterium paragallinarum in experimentally infected birds. Indian J. Vet. Pathol. 2013.
2. Akhter S, Ali M, Das P.M, Hossain M.M. Isolation and identification of Avibacterium paragallinarum, the causal agent of infectious coryza (IC) from layer chickens in Bangladesh. J. Bangladesh Agric. Univ. 2013.
3. Durairajan R, Sharma M, Murugan M.S. Detection of Avibacterium paragallinarum in commercial poultry and their antibiogram. Tamil Nadu J. Vet. Anim. Sci. Res. 2013.
4. Patil V.V, Mishra D.N, Mane D.V. Isolation, characterization and serological study of Avibacterium paragallinarum field isolates from Indian poultry. J. Anim. Poult. Sci. 2016.
5. Blackall P.J, Soriano-Vargas E. Infectious coryza and related bacterial infections. In: Swayne D.E, Pattison M, Mc Mullin P.F, Bradbury J.M, editors. Disease of Poultry. 13th ed. Ch. 20. India: John Wiley and Sons; 2013.
6. Chukiatsiri K, Sasipreeyajan J, Blackall P.J, Yuwatanichsampan S, Chansiripornchai, N. Serovar identification, antimicrobial sensitivity, and virulence of Avibacterium paragallinarum isolated from chicken in Thailand. Avian Dis. 2012.
7. Dungu B, Brett B, MacDonald R, Deville S, Dupuis L, Theron J, Bragg R.R. Study on the efficacy and safety of different antigens and oil formulations of infectious coryza vaccines containing an NAD-independent strain of Avibacterium paragallinarum. Onderstepoort J. Vet. Res. 2009.
8. Chukiatsiri K, Sasipreeyajan J, Neramitmansuk W, Chansiripornchai N. Efficacy of autogenous killed vaccine of Avibacterium paragallinarum. Avian Dis. 2009.
9. Dungu, B., Brett, B., et al., Study on the efficacy and safety of different antigens and oil formulations of infectious coryza vaccines containing an NAD-independent strain of Avibacterium paragallinarum. Onderstepoort J.Vet. Res.
10. Chukiatsiri, K., Sasipreeyajan, J., et al., Efficacy of autogenous killed vaccine of Avibacterium paragallinarum. Avian Dis. 2009.
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