ButiPEARL - Encapsulated Butyric Acid for a Healthy Gut

ButiPEARL, an encapsulated source of butyric acid for livestock and poultry, is manufactured using a proprietary spray freezing process. MicroPEARLS® spray freezing technology allows for targeted release all along the gastrointestinal (GI) tract, promoting an efficient use of butyric acid in swine and poultry. The encapsulation process also greatly reduces the odor typically associated with butyric acid.

Role of Butyric Acid for Livestock and Poultry

Butyric acid is one of the short-chain fatty acids (SCFA) most efficiently used by the epithelial cells of the GI tract. Butyric acid promotes the growth of tissues lining the GI tract and development of the intestinal epithelium in monogastric animals.1,2 With pressure from customers to reduce the use of antibiotics, encapsulated butyric acid has become a first-choice antibiotic alternative for broiler and swine producers. Delivery of butyric acid to the small intestine can improve the tight junctions, strengthening the intestinal barrier with upregulation of tight junction proteins. By strengthening the barrier and aiding in barrier recovery, encapsulated butyric acid can reduce the impact of environmental and pathogenic challenges.

Benefits of Butyric Acid for Livestock and Poultry

  • Antibiotic alternative for broilers and swine
  • Cellular signaling to enterocytes1
  • Improves tight junctions in the intestines2
  • Increases antioxidant levels to promote healing in the GI tract2
  • Improves intestinal development3
  • Modulates immune response4
  • Reduces inflammation4

MicroPEARL Technology—Delivering Encapsulated Butyric Acid for Optimum Utilization

A fat matrix encapsulates the butyric acid ensuring the MicroPEARL is not digested immediately; it is the delivery system for the active material. Particles of butyric acid salt are embedded in the MicroPEARLS matrix during the manufacturing process. Particles are released in the presence of an aqueous environment, leaving holes to new, unexposed particles.

Liquid enters the MicroPEARL through exterior holes, where it then comes into contact with the other particles of butyric acid. These particles are then released, leaving new holes as liquid contacts them. In the end, the MicroPEARLS look like empty shells. The released material disassociates into butyric acid and calcium. The butyric acid can then be utilized to support efficiency, performance and growth all along the intestinal tract.

Commitment to Quality and Food Safety

Since earning the prestigious Global Food Safety Initiative (GFSI) recognition at its Des Moines, Iowa, manufacturing facility in February 2013, Kemin Industries has remained a leader in the production of safe, quality ingredients. the recognition reinforces the company's investment in human and financial capital to enhance existing conditions and processes, verifying its products are safe, efficient and effective until they reach the end consumer. Kemin has the FSSC 22000 certification, recognized by GFSI, which is accepted by food manufacturers worldwide.

Solution Driven, Customer Committed

Kemin offers a range of nutritional solutions for raising healthy animals. Kemin understands our customers desire to raise healthy livestock and poultry, giving consumers the nutritional and health benefits they are looking for, while also turning a profit. Kemin offers products and services to help with gut health, nutrition, feed quality and pathogen control for today's competitive marketplace.




1Peng, L., et al. 2009. Butyrate Enhances the Intestinal Barrier by Facilitating Tight Junction Assembly via Activation of AMP-Activated Protein Kinase in Caco-2 Cell Monolayers. J. Nutr. 139:1619-1625.

2Ma, X., et al. 2012. Butyrate promotes the recovering of intestinal wound healing through its positive effect on the tight junctions. J. Anim. Sci. 90 Suppl. 4:266-268.

3Kotunia, A., et al. 2004. Effect of sodium butyrate on the small intestine development in neonatal piglets fed by artificial sow. J. Physiol. Pharmacol. 55 Suppl. 2:59-68.

4Guilloteau, P., et al. 2010. From the gut to the peripheral tissues: The multiple effects of butyrate. Nutr. Res. Rev. 23:366-384.