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MetiPEARL - Rumen Protected Methionine

Encapsulated Methionine is Changing the Way Dairy Cows are Fed

Methionine is one of the first two limiting amino acids for milk and milk component production in North American dairy diets. It is an essential amino acid used as a building block for proteins, therefore, meeting your cow's methionine requirements is fundamental to the health and wellness of the dairy cow. Forages, feedstuffs and dietary intakes are extremely variable in the amount of metabolizable methionine (MP Methionine) supplied, which can negatively impact milk and milk component production.

MetiPEARL combines ruminal escape with high intestinal digestibility, resulting in one of the most cost-effective sources of MP Methionine for dairy cattle on the market. Meeting MP Methionine requirements using a rumen protected form can help optimize production and allow for greater flexibility when formulating rations. MetiPEARL is encapsulated using the company's proprietary MicroPEARLS® spray freezing process, which delivers the nutrients to the right place at the right time.

Keys for Selecting the Best Rumen Protected Methionine

First, product efficacy needs to be verified. Kemin has completed research to validate MetiPEARL efficacy. A bioavailability trial was conducted at the University of Delaware in which MetiPEARL and USA Lysine® were fed and their bioavailability values were calculated. This trial indicates MetiPEARL has a bioavailability of 30.5 percent, which means for every 100 grams of MetiPEARL fed, 30.5 grams of MP Methionine are supplied. On a per pound basis, this calculates to almost 139 grams of MP Methionine, which is more than what is calculated by nutritional software programs. 

Next, you need to compare the rumen protected methionine products available on the market. Kemin recommends examining the following product characteristics:

  • Methionine concentration: Percent (by weight) of the product that is methionine
  • Rumen escape: Percent of the methionine contained by the product that is undegraded in the rumen
  • Intestinal availability: Percent of undegraded methionine in a form available for absorption in the intestine of the animal
  • Metabolizable methionine (MP Methionine): Percent of the total methionine contained in the product available and utilized by the animal
    (100% x Rumen Escape % x Intestinal Availability % = Metabolizable Methionine %)


After comparing these product characteristics, determine what really matters: cost per gram of MP Methionine. See the chart below for a comparison of rumen protected methionine products available in the market. 

Figure 1. Comparisons of the rumen protected methionine products on the market

Delivering the Same Nutritional Value at a Lower Cost

High rumen escape alone does not deliver an adequate volume of available methionine to the cow. Each characteristic (methionine concentration, rumen escape, intestinal availability and metabolizable methionine) must be considered when determining which product provides the most cost-effective supply of MP Methionine. When taking these characteristics into account, MetiPEARL is a cost-effective source of MP Methionine. 

See the table below for a price comparison of the rumen protected methionine products available in the market. 

Table 1. Price comparison of rumen protected methionine products

  Grams of MP Methionine/
lb of Product
 Product Cost 
MP Methionine Cost
 ($/gram of MP Methionine) 
Product 454 grams of product x 
 % methionine x % MP Methionine 
  ($/lb of product) / 
(grams of MP Methionine)
MetiPEARL 129 $3.00 $0.023
Smartamine® M 257 $7.00 $0.027
Mepron® 189 $4.90 $0.026
MetaSmart® Dry 100 $2.77 $0.028
MetaSmart® Liquid  167 $3.98 $0.023


Product Specifications

MetiPEARL Spec Sheet


Commitment to Quality and Food Safety

Since earning the prestigious Global Food Safety Initiative (GFSI) recognition at its Des Moines, Iowa, manufacturing facility in February 2013, Kemin Industries remains a leader in the production of safe, quality ingredients. The recognition reinforced the company's investment in human and financial capital to enhance existing conditions and processes, verifying its products are safe, efficient and effective until they reach the end consumer. Kemin has the FSSC 22000 certification, recognized by GFSI, which is accepted by food manufacturers worldwide. 


Smartamine® M and MetaSmart® are registered trademarks of Adisseo France S.A.S.

Mepron® is a registered trademark of Evonik Industries.

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