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CLOSTAT® Active Microbial for Poultry: Knock Out Pathogenic Bacteria for Improved Gut Health

CLOSTAT® contains a unique, patented spore-forming strain of Bacillus subtilis, PB6 which was isolated from chickens who had survived a high exposure to Clostridium perfringens in the environment. PB6 attacks and kills Clostridia and other pathogenic bacteria which can negatively impact the gastrointestinal (GI) tract. Because PB6 is a spore forming bacteria, it is compatible with most other ingredients and is able to survive harsh conditions, such as the acidity of the stomach or the temperatures associated with pelleting. With multiple product delivery options, CLOSTAT is the industry leader in reducing intestinal pathogen colonization leading to sickness in poultry. 

How CLOSTAT Works

CLOSTAT® Mode of Action

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Product

Description

Inclusion Level

CLOSTAT® Concentrate

For use in vitamin or trace mineral premixes

1.5 g / finished ton of feed

CLOSTAT® 500

For use in vitamin or trace mineral premixes or feed mills capable of small quantity additions through micro machines

25 g / finished ton of feed

CLOSTAT® Dry

For use in feed mills

1 lb / finished ton of feed

CLOSTAT® Green

Suitable for organic production use via delivery through feed

1 lb / finished ton of feed

CLOSTAT® WS

For use in drinking water applied through a water medicator

1 packet / 5-gallon stock solution metered out 1:128

CLOSTAT® Green HC SP

Suitable for organic production use in drinking water via delivery through a water medicator system

161 g (approx. 5 scoops) / 5-gallon stock solution metered out 1:128

 

Product Specifications

CLOSTAT® Dry Spec Sheet

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Resources

The Effect of a Water Soluble Active Microbial on Broiler Performance

 

In order to increase the customer's flexibility of PB6 delivery, a water-soluble product was developed to co-exist with CLOSTAT® Dry for feed. CLOSTAT® WS is delivered through the water via a medicator and does not require any diet formulation changes. This increases the ability to target houses with historic necrotic enteritis breaks. A study was conducted to evaluate the effect of PB6 when delivered in a water soluble (WS) form at different concentrations on the performance and health parameters in broilers in a necrotic enteritis challenge model.

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