Effect of NSAIDs on Gastric Ulceration, Markers of Intestinal Inflammation, and Fecal Microbiota in Horses

Presented as part of the KEMTalk Webinar Series by Dr. Canaan Whitfield, Associate Professor of Large Animal Surgery with Texas A&M Veterinary Medicine and Biomedical Sciences.

Dr. Whitfield graduated from the University of Georgia, College of Veterinary Medicine. After graduation, he completed a large animal internship at the University of Georgia followed by an equine surgery residency at Texas A&M University. Dr. Whitfield then worked in a private equine practice in South Carolina and Texas, primarily performing equine surgery and sports medicine. Following three years in practice, he returned to Texas A&M University as a doctoral student and received a PhD in biomedical sciences in 2016, eventually assuming his current position.

Dr. Whitfield’s clinical and research interests include wound healing and gastrointestinal healing, with a specific focus on how the microbiota influences gastrointestinal health and response to injury.

Q&A Breakout

Question 1: Do you think myeloperoxidase fecal assay could be a useful tool for equine practitioners?

Question 2: If a horse receives NSAID treatment long-term (several days or more), would you recommend a concurrent course of UlcerGard/GastroGard? And has that been studied, to your knowledge?

Question 3: ...follow up to my UlcerGard question - recognizing that it may not be as helpful for glandular ulcers, what might you recommend to manage animals in this regard to help minimize ulcer severity?

Question 4: Is NSAID's creating a form of leaky gut?

Question 5: Did you look at butyric acid with NSAID's and did you see any changes?

Question 6: Would you share what your future looks like for next year?

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