Coccidiosis and Economic Losses

Avian Coccidiosis negatively impacts intestinal integrity, leading to a decrease in bird’s health and proper functioning of the digestive system, which can lead to severe economic losses. Economic losses due to Coccidiosis worldwide has been estimated to be in the range of $3 billion due to decreased productivity in poultry.3.,6 A study conducted by A.K. Berra et. al., (2010) revealed that 68 percent of losses due to Coccidiosis were as a result of reduction in body weight, and 23 percent were due to increased feed conversion ratio.

Coccidiosis is caused by protozoan parasites belonging to the Eimeria genus. It is characterized by dysentery, enteritis, poor growth, emaciation, drooping wings, poor growth, low production1 with high rate of mortality and morbidity.4 The most common Eimeria spp. for poultry are E. acervuline, E. tenella, E. maxima.5 The different species affect specific parts in the intestine as shown in the picture below.


Image: Different Eimeria spp. region of occurrence within the poultry intestinal gut.

Mode of Action

The active ingredient (THB) in COZANTE™ causes a disruption of the cell wall of sporozoites, the pathogenic stage of Eimeria spp. leading to cell death. Kemin uses proprietary encapsulation spray freezing technology (SFT) in to ensure the sustained release of the COZANTE active ingredient throughout the length of the intestine.



  • Assists in the control of Coccidiosis in poultry
  • Encapsulated 3, 4, 5 – Trihydroxybenzoic Acid (THB)
  • Sustained release of the active ingredient throughout the intestine
  • Active against all three major Eimeria species in broilers, E. acervuline, E. maxima and E. tenella
  • Compatible with commonly used feed additives, including Tiamulin
  • Used in anticoccidial shuttle programmes

For more information on COZANTE, please contact +27 11 206 8000.


1. Awais M et al. 2012, Seasonal prevalence of Coccidiosis in industrial broiler chicken in Faisalabad, Punjab , Paskistan, Trop Ani Health production , 44 (2): 323-8

2. Bera, A.K. 2010, Evaluation of Economic Losses due to Coccidiosis in Poultry Industry in India, Agricultural Economics Research Review Vol. 23 January-June 2010 pp 91-96

3. Dalloul and Lillehoj, 2006, Poultry coccidiosis: recent advancements in control measures and vaccine development February 2006, Vol. 5, No. 1 , Pages 143-163 

4. Shirzad M et al. 2011, Prevalence and risk factors for subclinical Coccidiosis in broiler chicken farms in Mazandaran province, Iran, Trop. Animal health production 43: 1601-04

5. Venkateswara Rao, 2012. Speciation of Poultry Eimeria by morphology and SCAR PCR in Southern India. Indian Journal of Animal Sciences, 82(8): 805-811 

6. Williams, R.B. ,1999 A compartmentalized model for the estimation of the cost of coccidiosis to the world’s chicken production industry, International Journal of Parasitology, 29: 1209-1229