Aleta™ – Immune Modulation

It’s a golden rule of animal production: Healthy animals are more likely to provide higher production efficiency and economic profitability. Whether cattle, swine, poultry or aqua, supporting an animal’s immunity, disease resistance and overall health improvement can have far reaching benefits for animal producers worldwide.

Aleta is a pure and highly bioavailable immunomodulator which provides a high and consistent concentration of beta-1,3-glucan to improve immunity and animal performance. Serving as an immunomodulator in animals, the algae-based solution can be a cost-effective way to manage immunosuppression from disease and stress, and replace antibiotic growth promoters (AGPs).

Aleta advantages:

  • Improves immunity
  • Helps animals resist disease
  • Anti-inflammatory
  • Increases production performance parameters
    • Feed Conversion Ratio (FCR)
    • Body weight
    • Reduction in mortality
  • Replaces Antibiotic Growth Promoters              

Beta Glucans and Their Bioavailability

The most common source of beta glucans has been the cell wall of Saccharomyces which produces branched beta glucans. In contrast, Aleta is produced via a process that makes linear beta glucans. It is also more cost effective to produce Aleta than that of the traditional yeast-derived beta glucans.           


Aleta is produced from Euglena gracilis, a unique alga which contains more than 50 percent beta-1,3-glucan. These algal cells are highly digestible, making this Aleta’s beta glucan bioavailable without extraction.

chemical structure

Nonspecific Immune Modulation

Disease outbreaks are still a costly factor in the food animal industry, despite improvements in management practices and availability of vaccines against infectious diseases in food animals

Economic losses are seen with these examples of modern disease outbreaks:

  • Bacterial enteritis and coccidiosis in poultry cause the broiler industry billions of dollars in economic losses.
  • White Spot Syndrome Virus (WSSV) is a highly contagious and lethal pathogen also known as one of the most economically devastating viruses in the shrimp industry.1
  • Bovine Respiratory Disease caused $2 to 3 billion economic losses for the U.S. cattle industry. This outbreak caused reduced growth performance and increased treatment costs.2
  • Mastitis in ruminants causes the U.S. dairy industry $2 billion in losses each year; with 70 percent of this economic loss due to a reduced milk yield.3

As an immunomodulator in animals, Aleta can help producers manage these types of losses. By boosting nonspecific immune modulation, Aleta heightens an animal’s immunologic capabilities when an animal may be exposed to one or more pathogens or be compromised immunologically.

Aleta’s nonspecific immune modulation can potentiate the immune response during:

  • The neonatal period when the immune system may not be fully developed
  • High production periods such as peak of lay for layers at 30 weeks of age, lactation and gestation for sows.
  • Stress-induced immunosuppression that includes high stocking densities, heat stress, vaccination and handling of livestock and during harvesting of aquaculture.
  • Transferring of pullets from rearing to laying farms (14-17 weeks of age).
  • Pathogen-induced immunosuppression (virus, bacteria or protozoa)
  • Antibiotic reduction programs. With proper farm management and improved biosecurity, novel feed additives are helpful in reducing prophylactic as well as therapeutic use of antibiotics.

For more information on Aleta, please contact +27 11 206 8000.


1. Ramos-Carreno et al., 2014

2. Fulton (2009); Irsik (2006)

3. National Mastitis Council, 1987